Disinfectant emulsion



Patented July 14,

UNITED. TA

vmsnvrno'mu'r EMULSION A mos Edison Badertscher. Baltimore, -Md., as- L *signor to McCormick and Company, Inc., Baltimore, Md., a corporation Maryland [no Drawing. Application March 24,1941,

Serial 1w. 384,959 a My invention relates sinfectants, particularly emulsionsof the oill water. type which are stable and have improvedjgerm killing. power.

Heretofore use has beenimade of aqueous sus pensions of phenols as disinfectants} fungicidal and-insecticidal productsbiitithas been difiicult' to produce stable mixtures'fwhich can be stored and diluted without encountering flaking, crystal} lizing or separating out otthe chemical ingredients. Further, when ernpldying solid phenol compounds it has been necessary to use very ffinely divided particles so that-[the compound can be readily dispersed. throughout the mixture. This increases the productionjfcost. Moreover, the stability of the product i sjnot improved.

Insecticidal compositions have been made heretofore comprising orthophenylphenol which are adapted to be stirred in otwater to form temporary suspensions .but-flthese compositions are notcompoundecl so as to prevent or inhibit the crystallizing out of the orthophenylphenol.

Ihave discovered that.;disinfecta-nt emulsions of'improved stability and germ killing efllciency can be made utilizing 'orthophenylphenol as the principal disinfectant ingredient 3 After considerable research and the formulating and testing of a large number of compositions I have discovered. that emulsions of orthophenylphenol can be made which are relatively stablebyincorporating terpene ether with orthophenylphenol. Germicidalemulsions made according to my inventiorifb'y combining terpene chemical ingredientsare incorporated with sul- .phonated castor oil or a similar oil-wateremulsifying agent to form an efficient disinfectant. My experiments indicate that the terpene ether and orthophenylphenol act synergistically, and prethey remain uniformly dispersed throughoutthe vehicle forming an improved disinfectant emul dilution with water.

11 Claims. (01. 167--31) so-called Turkey red oil, which was utilized contained approximately 25% water, about 25% .saponified oil and the remainder of the oil was Sulphonated. This oil forms an emulsion in water. In the example given it was noted that a sulted ina few days and an unstable emulsion was formed on dilution with water. 1 Moreover the formulation of Example I did not possess the required phenol coeflicient. This should be approximately 8 when tested by the Food and Drug Administration test utilizing the organism Eberthella tzmhosa.

Sulphonated castor .oil 80 This emulsion appeared to be more stable upon When orthophenylphenol was increased 20% this showed slight flaking out of the chemical upon standing and upon dilution with water.

Example III Per cent Orthophenylphenol 20 Isopropyl alcohol 10 Steam distilled pine oil 10 Sulphonated castor oil 60 Example IV i Per cent Orthophenylphenol 30 Steam distilled pine oil 1f Isopropyl alcohol .10 Sulphonated castor oil. 50

. vent crystallizing outof the compounds so that 40 sion. This is the principal object of my inveni tion. i l

1 Typical examples of disinfectant emulsions compounded according to my invention have the following composition by weight: T

Example! v i w U Per cent Orthophenylphenol 10 Sulphonated castoroil 90 The orthophenylphenol is preferably incorporated in the sulphonated .castor oil as a liquid. The disinfectant material orthophenylphenol is nto stable upon standing but when diluted a small amount of oil separated out on top. When tested by the above mentioned 'F'. D. A. method the phenol coeflicient was somewhat above 8 on E.

typhi.

In order to provide a more stable emulsion and eliminate the odor of. pine oil the following coinpositions were'formulated:

Example V Per cent Orthophenylphenol 10 'I'erpene ether 10 Sulphonated castor oil 80 Thi s composition had a phenol coeiiicient of 2.5 on E. typhi by the F. D. A. method.

Example VI Per cent Orthophenylphenol 15 Terpene ether.. s 10 Sulphonated castor oil ether and 65% sulphonated castor oil.

. separate out even ,to keep the orthophenylphenol and separating out with.water.

' 'sulphonated castor tion may bediluted at therate oi one ounce ol' disinfectant emulsion to one gallon of water'and will retain its germ H of thirty. days, The combined use of terpene This composition.

5 on E. typhi bythe F. D. A. method. Example VII Per cent Orthophenylphenol 20 Terpene ether '10 Sulphonated castor oi1- '70' This composition had a had a phenol coefficient t phenol coefficient of f "with another group and ,need not bein pure form.

understood that other hydroxybiphenyls may be utilize1:i in-placeof orthophenylphenol. The terpene ethers-. used are characte'riz ed iby'containing an ether linkage connecting the terpeni'c group the terpene compounds In'place'of-sulphonated castor oil other sulphonated fatty-oils may be utilized as well as sulphite waste liquor'and the like wetting and emulsifying agents. In addition, inert fillers such as diatom aceous earth, bentonite, chalk and the T like may be incorporated to provide a composition "This composition had a phenol coettlcient oi:

9 011 1 *typhi bythe- D. A. method.

v Escaniple IX H ''Per cent Orthophenylphenol 30 Terpene:ether' 10- sulphonatedjc'astor 0il' 60 "This-composition had a phenol I2 .on typhi bythe F. D. A. method, I I

Example X Y Per cent Orthophenylphenol 40 Terpen ether 10 Sulphonated castor oil 5 0 In this example the composition hada phenol coeiiticientof; 13 on Eatyphi by the F. D. A. method? j "Allrof the emulsions formulated as in Examples V to X- were stable and the formula having a phenol coefficient closest to 8 by the F. D. A. method on E. typhi was that of Example VIII comprising 25% orthophenylphenol, 10% terpene Stock emulsions made up according to Example VIII were stable and the orthophenylphenol did not when the emulsion was diluted after storage. If desired the amount of terpene ether may be varied betweena range of e. g. 5%- %"although I have found that 10% gives the best results.

= Orthophenylphenol has a phenol coefficient of 26 on the F. D.. A.

testedby the same the same organism; In viewof this pene ether aside from the ia'ct from cry'stallizing when the emulsion is'diluted .Ihavetherefore discovered an improved disinfectant emulsion" utilizing orthophenylphenol and terpene ether which-is: stable and very efficient. Theproduct produced comprising orthophenylphenol, terpene ether and oil, according to my invenkilling eff ciency rorj afiperiod ether with orthophenylphenol resulted in unexpectedly producing a very stableand highlyactive germ killing disinfectant. combination of phenol and ether compounds performs the dual function of rendering the emulsion more stable and serving to tallizing tendency of the h v The compositions illustrated in the are merely typical formulations and orthophenylphenol.

examples it will be coefficientjof The particular phenylphenol, terpene method on Evtyphi and the agent, said composition having "a phenol .co-

formula containing 25% orthophenylphenol has a phenol coefficient of 9 when method onl ..there is an added advantage in using 10% terthat it'functions bein least, F-

' beingat least 8jby 'phenylphenol, terpene ether,

having the desired consistency.

Further, it will be appreciated that in the above examples the particular amounts of the ingredientsimay' be varied somewhat as to the relative proportions, so emulsion product is formed eflicient of approximately B'by the D.:A'. method E. typhi. f h.

Itl'will be understood'further that the examples. herein set forth are merely illustrative and that they may be varied to suit different conditions.

; and uses to whichmy invention-'is'to be used without departing broadly from the spirit and the scope of my invention as defined by'the appended Havingjthus full described my inventiomwhat I claim as new and desire to secure-by Letters Patent,is:'"" I 1. IA disinfectant composition comprising an ether of, terpene, hydroxybiphenyl, and an emulsifying agent, said composition having a phenol coefli'cient exceeding the aggregate coeflicient of the individual ingredients thereof.-'

. 2. A disinfectantcomposition co mprising orthoand an. emulsifying agent'Qsaid composition having a phenol'coefficient exceeding the aggregate coetllcient of-the individual ingredients thereof.

. 31 A'disinfectant"composition in the form of an emulsion comprising" orthophenylphenol and terpene ether, said composition 'having a phenol coeflic'ient exceeding" the aggrgatecoefficient of the individual ingredients thereof, said coefficient the ED: A. method on E. typhi.

4. A disinfectant emulsiod comprising or-tho" ether; and an emulsified eff cient exceedingthe aggregate coefificient of the "thereof,- said coefficient D." method. on .E.

individual ingredients .5Q A disinfectant"fcomposition'comprising an emulsion of a phenylphenol compound and a terpenejether, said composition havinga phenol [coefficient exceeding {the aggregate coefficient of the individual ingredients thereof,-'said'coefficient inhibit the crysweight 10% .to

being at leastfi by the F. D. ty hi.

A. method on E.

6. A disinfectant composition comprising an emulsion of terpene thr and' 'a' phenylphenol compound, said phenylphenol being incorporated to produce a phenol coefficient of I approximately 1. 8.; .as'wtested by the F. D. A.- method onE. -;tl/1 hi,;= said amount of --phenylphen 0l being perse nsufficient topr oduce said-phenol coefficient.

--'l'. A qdisinfectant emulsion". by v40% iorthophenylphenol, 5% to 15% terpene, ether and the remaindei" sulphonatedcastor oil.

8 -A.disinf.ectant emulsion co mprising by weight 25 .orthophenylphenol, 65% sulphonated cas'toroil.

terpene ether and long as a stapl disinfectant having a. Jphenol co- 9. A disinfectant composition comprising an emulsifying agent, orthophenylphenol and terpene ether in amount sufficient toproduce a composition having a phenol coefficient of ap proximately 8 by the F. D. A. method on E. typhi, said coeflicient being greater than the aggregate coeflicient of the individual components of said composition.

10. A disinfectant emulsion comprising orthophenylphenol, terpene ether, sulphonated fatty oil, said sulphonated fatty oil comprising a'major constituent and including orthophenylphenol to produce a disinfectant having a phenol coefficient phenylphenol, terpene ether of approximately 8 by the F. D. A. method on E. typhz'. V 11. A disinfectant emulsion comprising orthoand an emulsifying agent, said terpene ether being incorporated in an amount sufiicient to inhibit the crystallizing out of the orthophenylphenol constituent, and

said emulsion having a phenol coefficient greater than the aggregate of the individual components thereof, said coefficient being at least 8 by the F. D. A. meth0d on E. typhi.

A. EDISON BADERTSCHER. 

